Free Republic

In emergency rooms and intensive care units across the country, clinicians make split-second decisions about which antibiotics to give a patient. A new study reveals that these decisions may have unintended consequences for patient outcomes. Beginning in 2015, a 15-month national shortage of a commonly prescribed antibiotic, piperacillin/tazobactam--known by the brand name Zosyn--provided a unique opportunity to compare rates of death in hospitalized patients with sepsis who were administered two different types of antibiotics—one that spares the gut microbiome and one that profoundly alters it. Piperacillin/tazobactam is a broad-spectrum antibiotic that is commonly administered for sepsis, a life-threatening complication from...

A retired sidekick of General Michael Flynn, O-6 Ret Special Forces officer Ivan Raiklin discusses with NPR journalist what is about to happen with all of those people who set up Gen Flynn, Trump, and many others. https://twitter.com/IvanRaiklin/status/1790813699655061952

Has anyone here had LASIK eye surgery, and have you been happy with the results? I'd especially like to hear from those who have had it on one eye. I have one eye that is very good, and one with astigmatism that seems to get worse as I age. I'm thinking of having Lasik on the bad eye. Thanks very much to anyone who has the time to reply.

For the roughly 150,000 AIDS patients who come down with a life-threatening infection called fungal meningitis each year, there's only one treatment: a drug called fluconazole that works for less than half of patients. Now, a study suggests there may be a way to improve the odds—simply by changing what patients eat. In animal tests, the researchers found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus than taking the medication alone. For the new study, the researchers wondered if a keto diet—which deprives the body of glucose by cutting carbohydrate...

Researchers have made a discovery that could bring relief to those struggling with long COVID. In a world-first finding, they've identified a way to restore the faulty function of ion channels on immune cells using a well-known drug. The breakthrough, builds on previous research showing long COVID patients share similar issues with ion channels as those with chronic fatigue syndrome (also known as myalgic encephalomyelitis or ME/CFS). The team had previously shown success in restoring ion channel function in ME/CFS patients using a drug called Naltrexone, and now they've achieved similar results with long COVID patients. "Ion channels are integral...

Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health. Intestinal microbes metabolize dietary components into beneficial fatty acids (FAs), supporting metabolism and maintaining host body homeostasis. Metabolites originating from polyunsaturated fatty acids (PUFAs), influenced by gut microbes such as Lactobacillus plantarum, exhibit potent effects on inflammation and immune responses. The researchers used antigen-stimulated spleen cells to elicit an enhanced immune response. Subsequently, they investigated the impacts of different polyunsaturated fatty acid (PUFA) derivatives, focusing on metabolites of linoleic acid, a prevalent dietary fatty acid. Their findings revealed...

Exercise prompts muscles to release molecular cargo that boosts brain cell function and connection, but the process is not well understood. New research has found that the nerves that tell muscles to move also prompt them to release more of the brain-boosting factors. "The molecules released from the muscle go into the bloodstream and then to the brain." said Hyunjoon Kong. "As we get older, we lose these neurons from the muscle," he said. The researchers compared two muscle tissue models—one with neuron innervation and one without. They found that the innervated muscle produced more molecules that promote brain neuron...

There's a right name for the "Woke" ideology, and it's critical constructivism. Critical constructivist ideology is what you "wake up" to when you go Woke. Reading this book, which originally codified it in 2005, is like reading a confession of Woke ideology. Let's talk about it.

Terrence give his opinion on the NFL and it's not good.

,p> The Oklahoma State Bureau of Investigation and the U.S. Marshals Service found Jacob Mayhugh in Oklahoma City, according to OSBI. An arrest warrant was issued for Jacob in connection with the murders of James, Patty and Shayla Mayhugh.

Sens. Chuck Grassley and Ron Johnson are investigating whether Fulton County District Attorney Fani Willis’ office misused federal funds. The two Republican senators highlighted multiple reports accusing Willis’ office of squandering funds, including from the Justice Department Office of Juvenile Justice and Delinquency Prevention and other initiatives, on frivolous items such as “swag” and unrelated travel. “In Fiscal Year (FY) 2020, OJJDP awarded Fulton County nearly $500,000 to establish the Fulton County Center of Youth Empowerment and Gang Prevention,” Grassley (R-Iowa) and Johnson (R-Wis.) wrote in a letter to Willis Wednesday. “The Center has yet to open and the ‘building...

https://youtu.be/DnxEQ_oDhN4?t=151BEGIN TRANSCRIPT:Sky News host Rita Panahi, introducing the next video clip: Here is ABC host and Democratoperative George Stephanopoulos admitting that the Deepstate is real and it's beautiful Video clip of ABC News host George Stephanopoulos:These are people that come, they're relativelyyoung uh people who come from all overthe government, the CIA, the DIA, defensedepartment, military, and you know somepeople like to call those people theDeep State.Deep State, well the big thingI learned doing this book is that theDeep State is packed with patriots,people who go to work every single dayon the front lines of the most intensecrisis the country...

There is something that the establishment does not want you to know about ... and it's hidden in plain sight!

Have a Florida condo? Can you afford a $100,000 or higher special assessment for new safety standards? After the collapse of a Surfside Building on June 24, 2021that killed 98 people, the state passed a structural safety law that is now biting owners. Not only are insurance rates soaring, but owners are hit with huge special assessments topping $100,000.

The central African nation of the Democratic Republic of Congo (DRC) is battling a record number of cases of mpox, fueled by a strain with a higher death rate than the variant that spread in Europe and America in 2022. Getting the DRC outbreak under control, and containing it to within that country, is imperative, experts at the U.S. Centers for Disease Control and Prevention said in a report issued Thursday. The spread of the lethal clade I strain of mpox "raises concerns that the virus could spread to other countries and underscores the importance of coordinated, urgent global action...

The beloved British series "Doctor Who" did not live up to ratings expectations after its star told viewers not to watch if they had a problem with the progressive messaging of the show. Its cast, former lead, and director have been promoting progressive ideologies recently, while the show's viewership has been cut nearly in half. Lead actor and Doctor Who character Ncuti Gatwa already had the second-worst premiere for a season of "Doctor Who" in December 2023's Christmas special titled, "The Church on Ruby Road." According to the BBC, the episode had 4.7 million viewers. As That Park Place noted,...

There is little point in analyzing the bogus New York case against Donald Trump from a legal perspective because, of course, it’s not a legal matter. It’s a political matter. It’s a kangaroo court, an attempt to railroad a political opponent to keep him from winning the election against the desiccated, treacherous, corrupt old pervert whom he’s currently pummeling in the polls. But the legal realities are catching up to the people seeking to frame him. This isn’t a case. It’s a scam. A lie. A sham. And a disgrace, not that anything can be a disgrace in a system...

Boeing's Starliner flight to the International Space Station was delayed again due to a helium leak. NASA, Boeing and the United Launch Alliance said in a statemen Tuesday that the launch date will now come no earlier than Tuesday at 4:43 p.m. EDT. "Starliner teams are working to resolve a small helium leak detected in the spacecraft's service module traced to a flange on a single reaction control system thruster. Helium is used in spacecraft thruster systems to allow the thrusters to fire and is not combustible or toxic," they said. Boeing's statement said that it is working with NASA...

Five of the 10 highest-paid athletes in the world are soccer players, with Jon Rahm and LeBron James ranking as the top earners among non-soccer stars. Per Forbes' ranking of the 10 highest-paid athletes in 2024, Cristiano Ronaldo made more money than anyone with earnings of $260 million between his salary with Al Nassr and sponsorship deals. Here is the full top-10 list: Cristiano Ronaldo (Soccer): $260 million Jon Rahm (Golf): $218 million Lionel Messi (Soccer): $135 million LeBron James (NBA): $128.2 million Giannis Antetokounmpo (NBA): $111 million Kylian Mbappé (Soccer): $110 million Neymar (Soccer): $108 million Karim Benzema (Soccer):...

@SenLummis The Senate passing a CRA overturning SAB 121 is a win for financial innovation and a clear rebuke of the way the Biden admin and Gary Gensler have persecuted crypto. It also marks the 1st time Congress has passed standalone crypto legislation. We are just getting started.